Pattern and Atherogenic Index of Dyslipidaemia among Hypertensive Patients

Umuerri E.M.

Abstract



Objective: To describe the prevalence, pattern and atherogenic index of dyslipidaemia among hypertensive patients.

Method: Cross-sectional study of hypertensive subjects at first presentation in a community-based cardiology clinic in Delta State, Nigeria. The Delta State University Teaching Hospital Health Research Ethics Committee granted ethical approval for the study. Fasting serum lipid profile was retrieved and atherogenic indices calculated. Data analysis was done using SPSS version 23.0.

Result: The mean age of the 227 subjects was 55.4 (±13.6) years, and 111 (48.9%) were males. A total of 154 (67.8%) had at least one abnormal lipid profile level, out of which 56.5% were females (p=0.018). The pattern of dyslipidaemia [isolated (56, 36.4%), two-combined (65, 42.2%), and mixed (33, 21.4%)] did not differ by sex (p = 0.173).

The predisposition to high cardiovascular risk was predicted by atherogenic index of plasma (59.5%), atherogenic coefficient (43.6%), Castelli ratios I, II (29.1%, 26.9%).

Conclusion: The prevalence of dyslipidaemia was 67.8%. Two-combined dyslipidaemia was the most common pattern.

Keywords


Dyslipidaemia, atherogenic index, hypertension, prevalence, Nigeria

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